If you have Homebrew already, it should be immediately evident. Or, if you are the reckless or impatient sort, you can do what I did and press on by entering brew doctor into the terminal. ![]() I have only been diving into the dev game since the start of the year (and until today was only familiar setting things up on PC/Linux), so rather than potentially leading you astray, I suggest you check out for guidance on all things Homebrew. As was the case for me, there's a chance you may already have a version of Homebrew installed. It appears that version and the version instructed above are just two different roads leading to the same destination. Download and install BEDTools, samtools, tabix, and the UCSC tools bigWigSummary, bigWigToBedGraph, and bedGraphToBigWig Download and install Miniconda (a slimmed-down version of the Anaconda Python distribution) which sets up an isolated Python environment that is separate from anything you might already have installed (see Miniconda instead of virtualenv for more details on this). meaning I had installed Homebrew according to the instructions on their actual site. ![]() Prior to pasting the above into the terminal, I had used: Encountered that very same issue! For me, it was quickly resolved, though:
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